Clustering of α₅β₁ integrins determines adhesion strength whereas αvβ₃ and talin enable mechanotrans...
Clustering of α₅β₁ integrins determines adhesion strength whereas αvβ₃ and talin enable mechanotransduction
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Publisher
National Academy of Sciences
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Language
English
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National Academy of Sciences
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A key molecular link between cells and the extracellular matrix is the binding between fibronectin and integrins α₅β₁ and αvβ₃. However, the roles of these different integrins in establishing adhesion remain unclear. We tested the adhesion strength of fibronectin-integrin-cytoskeleton linkages by applying physiological nanonewton forces to fibronec...
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Full title
Clustering of α₅β₁ integrins determines adhesion strength whereas αvβ₃ and talin enable mechanotransduction
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TN_cdi_pnas_primary_106_38_16245_fulltext
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_38_16245_fulltext
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0902818106
