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Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_42_17886_fulltext

Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

About this item

Full title

Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

Author / Creator

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (42), p.17886-17891

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Despite 2 decades of research, no clear function for annexin A1 (AnxA1) has been established. Using AnxA1-KO mice, we show that tumor growth and metastasis are significantly decreased, whereas rodent survival and tumor necrosis are greatly increased when tumors grow in AnxA1-KO mice. Systems analysis of gene expression in these tumors specifically...

Alternative Titles

Full title

Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_42_17886_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_42_17886_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0901324106

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