Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice
Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Despite 2 decades of research, no clear function for annexin A1 (AnxA1) has been established. Using AnxA1-KO mice, we show that tumor growth and metastasis are significantly decreased, whereas rodent survival and tumor necrosis are greatly increased when tumors grow in AnxA1-KO mice. Systems analysis of gene expression in these tumors specifically...
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Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice
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TN_cdi_pnas_primary_106_42_17886_fulltext
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_42_17886_fulltext
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0901324106