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critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BX...

critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BX...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_5_1518_fulltext

critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

About this item

Full title

critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (5), p.1518-1523

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Interleukin 21 (IL-21) is a pleiotropic cytokine produced by CD4 T cells that affects the differentiation and function of T, B, and NK cells by binding to a receptor consisting of the common cytokine receptor γ chain and the IL-21 receptor (IL-21R). IL-21, a product associated with IL-17-producing CD4 T cells (TH17) and follicular CD4 T helper cell...

Alternative Titles

Full title

critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_5_1518_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_5_1518_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0807309106

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