Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the...
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Oxidative stress has been implicated in the etiology of Parkinson's disease (PD) and in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) animal model of PD. It is known that under conditions of oxidative stress, the transcription factor NF-E2-related factor (Nrf2) binds to antioxidant response element (ARE) to induce antioxidant and phase II...
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Full title
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
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TN_cdi_pnas_primary_106_8_2933_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_8_2933_fulltext
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0813361106
