Increased expression of leukotriene C₄ synthase and predominant formation of cysteinyl-leukotrienes...
Increased expression of leukotriene C₄ synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Leukotrienes (LTs) are arachidonic acid-derived lipid mediators involved in the pathogenesis and progression of diverse inflammatory disorders. The cysteinyl-leukotrienes LTC₄, LTD₄, and LTE₄ are important mediators of asthma, and LTB₄ has recently been implicated in atherosclerosis. Here we report that mRNA levels for the three key enzymes/protein...
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Full title
Increased expression of leukotriene C₄ synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm
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TN_cdi_pnas_primary_107_49_21093
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_107_49_21093
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1015166107
