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Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_107_5_2319

Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

About this item

Full title

Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (5), p.2319-2324

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

G protein-coupled receptors (GPCRs) are ubiquitous mediators of signaling of hormones, neurotransmitters, and sensing. The old dogma is that a one ligand/one receptor complex constitutes the functional unit of GPCR signaling. However, there is mounting evidence that some GPCRs form dimers or oligomers during their biosynthesis, activation, inactiva...

Alternative Titles

Full title

Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_107_5_2319

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_107_5_2319

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0906695106

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