Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation
Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
G protein-coupled receptors (GPCRs) are ubiquitous mediators of signaling of hormones, neurotransmitters, and sensing. The old dogma is that a one ligand/one receptor complex constitutes the functional unit of GPCR signaling. However, there is mounting evidence that some GPCRs form dimers or oligomers during their biosynthesis, activation, inactiva...
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Full title
Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation
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Record Identifier
TN_cdi_pnas_primary_107_5_2319
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_107_5_2319
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0906695106