Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive brea...
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
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Author / Creator
Shi, Lei , Sun, Luyang , Li, Qian , Liang, Jing , Yu, Wenhua , Yi, Xia , Yang, Xiaohan , Li, Yanyan , Han, Xiao , Zhang, Yu , Xuan, Chenghao , Yao, Zhi and Shang, Yongfeng
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
It is well-documented that the methylation of histone H3 lysine 4 (H3K4) and of H3K9 are mutually exclusive, an epigenetic phenomenon conserved from yeast to humans. How this opposed methylation modification is accomplished and coordinated in mammalian cells is poorly understood. Here we report that the H3K9 trimethyl demethylase JMJD2B is an integ...
Alternative Titles
Full title
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_108_18_7541
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_18_7541
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1017374108
