HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+T lymphocytes
HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+T lymphocytes
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
HLA-E is a nonclassical HLA class I molecule, which differs from classical HLA molecules by its nonpolymorphic, conserved nature. Expression and function of HLA-E in normal tissues and solid tumors is not fully understood. We investigated HLA-E protein expression on tissue sections of 420 ovarian and cervical cancers and found equal or higher level...
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Full title
HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+T lymphocytes
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TN_cdi_pnas_primary_108_26_10656
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_26_10656
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1100354108
