Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myoc...
Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion
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Author / Creator
Fauconnier, Jérémy , Meli, Albano C , Thireau, Jérôme , Roberge, Stephanie , Shan, Jian , Sassi, Yassine , Reiken, Steven R , Rauzier, Jean-Michel , Marchand, Alexandre , Chauvier, David , Cassan, Cécile , Crozier, Christine , Bideaux, Patrice , Lompré, Anne-Marie , Jacotot, Etienne , Marks, Andrew R and Lacampagne, Alain
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Myocardial ischemic disease is the major cause of death worldwide. After myocardial infarction, reperfusion of infracted heart has been an important objective of strategies to improve outcomes. However, cardiac ischemia/reperfusion (I/R) is characterized by inflammation, arrhythmias, cardiomyocyte damage, and, at the cellular level, disturbance in...
Alternative Titles
Full title
Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion
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Record Identifier
TN_cdi_pnas_primary_108_32_13258
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_32_13258
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1100286108