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Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myoc...

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myoc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_32_13258

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion

About this item

Full title

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (32), p.13258-13263

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Myocardial ischemic disease is the major cause of death worldwide. After myocardial infarction, reperfusion of infracted heart has been an important objective of strategies to improve outcomes. However, cardiac ischemia/reperfusion (I/R) is characterized by inflammation, arrhythmias, cardiomyocyte damage, and, at the cellular level, disturbance in...

Alternative Titles

Full title

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_108_32_13258

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_32_13258

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1100286108

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