Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell g...
Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth
About this item
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Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Epstein-Barr virus nuclear antigen 2 (EBNA2) regulation of transcription through the cell transcription factor RBPJ is essential for resting B-lymphocyte (RBL) conversion to immortal lymphoblast cell lines (LCLs). ChIP-seq of EBNA2 and RBPJ sites in LCL DNA found EBNA2 at 5,151 and RBPJ at 10,529 sites. EBNA2 sites were enriched for RBPJ (78%), ear...
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Full title
Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth
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Record Identifier
TN_cdi_pnas_primary_108_36_14902
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_36_14902
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1108892108
