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Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_39_16381

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

About this item

Full title

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16381-16385

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Insulin resistance is associated with nonalcoholic fatty liver disease (NAFLD) and is a major factor in the pathogenesis of type 2 diabetes. The development of hepatic insulin resistance has been ascribed to multiple causes, including inflammation, endoplasmic reticulum (ER) stress, and accumulation of hepatocellular lipids in animal models of NAFL...

Alternative Titles

Full title

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_108_39_16381

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_39_16381

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1113359108

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