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pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered mur...

pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered mur...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_46_E1164

pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast

About this item

Full title

pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (46), p.E1164-E1173

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

In most mammalian species, a critical step of placenta development is the fusion of trophoblast cells into a multinucleated syncytiotrophoblast layer fulfilling essential fetomaternal exchange functions. Key insights into this process came from the discovery of envelope genes of retroviral origin, the syncytins, independently acquired by the human...

Alternative Titles

Full title

pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_108_46_E1164

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_108_46_E1164

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1112304108

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