Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central me...
Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Adoptively transferred tumor-specific T cells offer the potential for non–cross-resistant therapy and long-term immunoprotection. Strategies to enhance in vivo persistence of transferred T cells can lead to improved antitumor efficacy. However, the extrinsic (patient conditioning) and intrinsic (effector cell) factors contributing to long-term in v...
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Full title
Transferred melanoma-specific CD8+ T cells persist, mediate tumor regression, and acquire central memory phenotype
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Record Identifier
TN_cdi_pnas_primary_109_12_4592
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_12_4592
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1113748109