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Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating AR...

Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating AR...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_26_10382

Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex

About this item

Full title

Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (26), p.10382-10387

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Regulation of actin dynamics is key to many cell physiological processes, ranging from protrusion formation and control of cell shape to cellular motility, endocytosis, and vesicle movement. The actin-related protein (ARP) 2/3 complex is a major actin nucleator organizing branched filament networks in lamellipodial protrusions and during cell migra...

Alternative Titles

Full title

Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_109_26_10382

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_26_10382

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1206468109

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