JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The c-Jun NH ₂-terminal kinase (JNK) signal transduction pathway is implicated in cancer, but the role of JNK in tumorigenesis is poorly understood. Here, we demonstrate that the JNK signaling pathway reduces the development of invasive adenocarcinoma in the phosphatase and tensin homolog (Pten) conditional deletion model of prostate cancer. Mice w...
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Full title
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate
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TN_cdi_pnas_primary_109_30_12046
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_30_12046
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1209660109
