Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphat...
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Lymphatic dissemination from the primary tumor is a major mechanism by which breast cancer cells access the systemic circulation, resulting in distant metastasis and mortality. Numerous studies link activation of hypoxia-inducible factor 1 (HIF-1) with tumor angiogenesis, metastasis, and patient mortality. However, the role of HIF-1 in lymphatic di...
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Full title
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
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TN_cdi_pnas_primary_109_40_E2707
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_109_40_E2707
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1214019109
