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IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_1_282

IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

About this item

Full title

IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.282-287

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Parasitic helminths are a major cause of chronic human disease, affecting more than 3 billion people worldwide. Host protection against most parasitic helminths relies upon Type 2 cytokine production, but the mechanisms that regulate interleukin (IL) 4 and 13 production from CD4⁺ R helper 2 cells (TH2) and innate lymphoid type 2 cells (ILC2s) remai...

Alternative Titles

Full title

IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_110_1_282

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_1_282

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1206587110

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