IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms
IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Parasitic helminths are a major cause of chronic human disease, affecting more than 3 billion people worldwide. Host protection against most parasitic helminths relies upon Type 2 cytokine production, but the mechanisms that regulate interleukin (IL) 4 and 13 production from CD4⁺ R helper 2 cells (TH2) and innate lymphoid type 2 cells (ILC2s) remai...
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Full title
IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms
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TN_cdi_pnas_primary_110_1_282
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_1_282
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1206587110