Structure and function of CarD, an essential mycobacterial transcription factor
Structure and function of CarD, an essential mycobacterial transcription factor
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
CarD, an essential transcription regulator in Mycobacterium tuberculosis , directly interacts with the RNA polymerase (RNAP). We used a combination of in vivo and in vitro approaches to establish that CarD is a global regulator that stimulates the formation of RNAP-holoenzyme open promoter (RPo) complexes. We determined the X-ray crystal structure...
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Full title
Structure and function of CarD, an essential mycobacterial transcription factor
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TN_cdi_pnas_primary_110_31_12619
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_31_12619
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1308270110
