Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA
Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Mammalian cells have evolved mechanisms to silence foreign DNA introduced by viruses or by transfection. Upon herpesviral infection of cells, the viral genome is chromatinized in an attempt by the host cell to restrict expression of the viral genome. HSV ICP0 acts to counter host-intrinsic and innate responses to viral infection. We have found that...
Alternative Titles
Full title
Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA
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TN_cdi_pnas_primary_110_47_E4492
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_47_E4492
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1316194110
