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Malaria life cycle intensifies both natural selection and random genetic drift

Malaria life cycle intensifies both natural selection and random genetic drift

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_50_20129

Malaria life cycle intensifies both natural selection and random genetic drift

About this item

Full title

Malaria life cycle intensifies both natural selection and random genetic drift

Publisher

United States: NATIONAL ACADEMY OF SCIENCES

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (50), p.20129-20134

Language

English

Formats

Publication information

Publisher

United States: NATIONAL ACADEMY OF SCIENCES

More information

Scope and Contents

Contents

Analysis of genome sequences of 159 isolates of Plasmodium falciparum from Senegal yields an extraordinarily high proportion (26.85%) of protein-coding genes with the ratio of nonsynonymous to synonymous polymorphism greater than one. This proportion is much greater than observed in other organisms. Also unusual is that the site-frequency spectra o...

Alternative Titles

Full title

Malaria life cycle intensifies both natural selection and random genetic drift

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_110_50_20129

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_110_50_20129

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1319857110

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