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Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from...

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_17_E1768

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

About this item

Full title

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (17), p.E1768-E1776

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A Streptococcus to unravel the nature and timing of molecular events contributing to the emergence, dissemination, and genetic diversification of an unusually virulent clone that now causes epidemic human infections worldwide. We discovered that the contemporary epidemic...

Alternative Titles

Full title

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_111_17_E1768

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_17_E1768

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1403138111

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