Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-in...
Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Celsr3 and Fzd3 , members of “core planar cell polarity” (PCP) genes, were shown previously to control forebrain axon guidance and wiring by acting in axons and/or guidepost cells. Here, we show that Celsr2 acts redundantly with Celsr3 , and that their combined mutation mimics that of Fzd3 . The phenotypes generated upon inactivation of Fzd3 in dif...
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Full title
Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner
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TN_cdi_pnas_primary_111_29_E2996
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_29_E2996
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1402105111
