EBV microRNA BART 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replica...
EBV microRNA BART 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replication in B cells
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
EBV is an oncogenic human herpesvirus that has the ability to infect and transform B cells latently in vitro. However, the virus also establishes a lifetime, benign, persistent latent infection in resting memory B cells in vivo, where the virus is quiescent (i.e., expresses none of the known latent proteins). The virus encodes ∼40 micro-RNAs (miRNA...
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Full title
EBV microRNA BART 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replication in B cells
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TN_cdi_pnas_primary_111_30_11157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_30_11157
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1406136111
