Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differ...
Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Pluripotency can be induced in somatic cells by overexpressing transcription factors, including POU class 5 homeobox 1 (OCT3/4), sex determining region Y-box 2 (SOX2), Krüppel-like factor 4 (KLF4), and myelocytomatosis oncogene (c-MYC). However, some induced pluripotent stem cells (iPSCs) exhibit defective differentiation and inappropriate maintena...
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Full title
Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential
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TN_cdi_pnas_primary_111_34_12426
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_34_12426
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1413299111
