A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER c...
A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Hepatic metabolism requires mitochondria to adapt their bioenergetic and biosynthetic output to accompany the ever-changing anabolic/catabolic state of the liver cell, but the wiring of this process is still largely unknown. Using a postprandial mouse liver model and quantitative cryo-EM analysis, we show that when the hepatic mammalian target of r...
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Full title
A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver
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Record Identifier
TN_cdi_pnas_primary_111_45_16017
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_45_16017
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1408061111
