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Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_46_16538

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

About this item

Full title

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (46), p.16538-16543

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Why different species are predisposed to different tumor spectra is not well understood. In particular, whether the physical location of tumor suppressor genes relative to one another influences tumor predisposition is unknown. Renal cancer presents a unique opportunity to explore this question. Renal cell carcinoma (RCC) of clear-cell type (ccRCC)...

Alternative Titles

Full title

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_111_46_16538

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_111_46_16538

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1414789111

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