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Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cell...

Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_26_E3421

Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells

About this item

Full title

Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (26), p.E3421-E3430

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Streptococcus pneumoniae is the most common cause of pneumonia, a leading cause of death globally. Limitations in antibiotic efficacy and vaccines call attention to the need to develop our understanding of host–pathogen interactions to improve mitigation strategies. Here, we show that lung cells exposed to S. pneumoniae are subject t...

Alternative Titles

Full title

Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_112_26_E3421

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_26_E3421

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1424144112

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