Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination
Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination
About this item
Full title
Author / Creator
Sanborn, J. Zachary , Chung, Jongsuk , Purdom, Elizabeth , Wang, Nicholas J. , Kakavand, Hojabr , Wilmott, James S. , Butler, Timothy , Thompson, John F. , Mann, Graham J. , Haydu, Lauren E. , Saw, Robyn P. M. , Busam, Klaus J. , Lo, Roger S. , Collisson, Eric A. , Hur, Joe S. , Spellman, Paul T. , Cleaver, James E. , Gray, Joe W. , Huh, Nam , Murali, Rajmohan , Scolyer, Richard A. , Bastian, Boris C. and Cho, Raymond J.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Melanoma is difficult to treat once it becomes metastatic. However, the precise ancestral relationship between primary tumors and their metastases is not well understood. We performed whole-exome sequencing of primary melanomas and multiple matched metastases from eight patients to elucidate their phylogenetic relationships. In six of eight patient...
Alternative Titles
Full title
Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination
Authors, Artists and Contributors
Author / Creator
Chung, Jongsuk
Purdom, Elizabeth
Wang, Nicholas J.
Kakavand, Hojabr
Wilmott, James S.
Butler, Timothy
Thompson, John F.
Mann, Graham J.
Haydu, Lauren E.
Saw, Robyn P. M.
Busam, Klaus J.
Lo, Roger S.
Collisson, Eric A.
Hur, Joe S.
Spellman, Paul T.
Cleaver, James E.
Gray, Joe W.
Huh, Nam
Murali, Rajmohan
Scolyer, Richard A.
Bastian, Boris C.
Cho, Raymond J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_112_35_10995
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_35_10995
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1508074112
