Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants
Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Broadly neutralizing anti–HIV-1 monoclonal antibodies, such as PG9, and its derivative RSH hold great promise in AIDS therapy and prevention. An important feature related to the exceptional efficacy of PG9 and RSH is the presence of sulfated tyrosine residues in their antigen-binding regions. To maximize antibody functionalities, we have now produc...
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Full title
Glycan modulation and sulfoengineering of anti–HIV-1 monoclonal antibody PG9 in plants
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Record Identifier
TN_cdi_pnas_primary_112_41_12675
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_41_12675
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1509090112
