Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell surv...
Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Short-term fasting protects mice from lethal doses of chemotherapy through undetermined mechanisms. Herein, we demonstrate that fasting preserves small intestinal (SI) architecture by maintaining SI stem cell viability and SI barrier function following exposure to high-dose etoposide. Nearly all SI stemcells were lost in fedmice, whereas fasting pr...
Alternative Titles
Full title
Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_112_51_E7148
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_112_51_E7148
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1509249112
