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The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_113_11_3054

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome

About this item

Full title

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (11), p.3054-3059

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes malignant and inflammatory diseases in ∼10% of infected people. A typical host has between 104 and 105 clones of HTLV-1–infected T lymphocytes, each clone distinguished by the genomic integration site of the single-copy HTLV-1 provirus. The HTLV-1 bZIP (HBZ) factor gene is const...

Alternative Titles

Full title

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_113_11_3054

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_113_11_3054

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1423199113

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