The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome
The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes malignant and inflammatory diseases in ∼10% of infected people. A typical host has between 104 and 105 clones of HTLV-1–infected T lymphocytes, each clone distinguished by the genomic integration site of the single-copy HTLV-1 provirus. The HTLV-1 bZIP (HBZ) factor gene is const...
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Full title
The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome
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TN_cdi_pnas_primary_113_11_3054
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_113_11_3054
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1423199113