Log in to save to my catalogue
Log in to save to my catalogue

Suramin inhibits cullin-RING E3 ubiquitin ligases

| Ask | Become a Library member

Suramin inhibits cullin-RING E3 ubiquitin ligases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_113_14_E2011

Suramin inhibits cullin-RING E3 ubiquitin ligases

About this item

Full title

Suramin inhibits cullin-RING E3 ubiquitin ligases

Author / Creator

Wu, Kenneth , Chong, Robert A. , Yu, Qing , Bai, Jin , Spratt, Donald E. , Ching, Kevin , Lee, Chan , Miao, Haibin , Tappin, Inger , Hurwitz, Jerard , Zheng, Ning , Shaw, Gary S. , Sun, Yi , Felsenfeld, Dan P. , Sanchez, Roberto , Zheng, Jun-nian and Pan, Zhen-Qiang

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-04, Vol.113 (14), p.E2011-E2018

Language

English

Formats

Articles

Publication information

Publisher

United States: National Academy of Sciences

Subjects

More information

Scope and Contents

Contents

Cullin-RING E3 ubiquitin ligases (CRL) control a myriad of biological processes by directing numerous protein substrates for proteasomal degradation. Key to CRL activity is the recruitment of the E2 ubiquitin-conjugating enzyme Cdc34 through electrostatic interactions between E3′s cullin conserved basic canyon and the acidic C terminus of the E2 en...

Alternative Titles

Full title

Suramin inhibits cullin-RING E3 ubiquitin ligases

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_113_14_E2011

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_113_14_E2011

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1601089113

How to access this item

Log in as a Library member

Full text available

About resource

View in old catalogue

Connecting people and collections