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Mutation Causing Temperature-Sensitive Expression of Cell Transformation by a Tumor Virus

Mutation Causing Temperature-Sensitive Expression of Cell Transformation by a Tumor Virus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_69_1_109

Mutation Causing Temperature-Sensitive Expression of Cell Transformation by a Tumor Virus

About this item

Full title

Mutation Causing Temperature-Sensitive Expression of Cell Transformation by a Tumor Virus

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1972-01, Vol.69 (1), p.109-114

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

A procedure has been devised to isolate 3T3 mouse fibroblasts transformed by simian virus 40 (SV40) that express their transformed phenotype at low (32 degrees C) but not at high (39 degrees C) temperature. Three parameters typical of malignant growth in vitro: (a) high saturation density in culture, (b) ability to form colonies on monolayers of no...

Alternative Titles

Full title

Mutation Causing Temperature-Sensitive Expression of Cell Transformation by a Tumor Virus

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_69_1_109

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_69_1_109

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.69.1.109

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