cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits
cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits
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Washington, DC: National Academy of Sciences of the United States of America
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Language
English
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Washington, DC: National Academy of Sciences of the United States of America
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Contents
The cGMP phosphodiesterase (PDE) of cattle retinal rod outer segments comprises three types of sub-units: the two heavy catalytic ones, PDEα and PDEβ , each around 85 kDa, and the light inhibitory one, PDEγ or I (11 kDa). The relative stoichiometry is usually assumed to be 1:1:1. PDE activation in the visual transduction cascade results from remova...
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Full title
cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits
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TN_cdi_pnas_primary_85_8_2424
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_85_8_2424
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.85.8.2424