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cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits

cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_85_8_2424

cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits

About this item

Full title

cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1988-04, Vol.85 (8), p.2424-2428

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

The cGMP phosphodiesterase (PDE) of cattle retinal rod outer segments comprises three types of sub-units: the two heavy catalytic ones, PDEα and PDEβ , each around 85 kDa, and the light inhibitory one, PDEγ or I (11 kDa). The relative stoichiometry is usually assumed to be 1:1:1. PDE activation in the visual transduction cascade results from remova...

Alternative Titles

Full title

cGMP Phosphodiesterase of Retinal Rods is Regulated by Two Inhibitory Subunits

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_85_8_2424

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_85_8_2424

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.85.8.2424

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