The Ligand Specificities of the Insulin Receptor and the Insulin-Like Growth Factor I Receptor Resid...
The Ligand Specificities of the Insulin Receptor and the Insulin-Like Growth Factor I Receptor Reside in Different Regions of a Common Binding Site
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences of the United States of America
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Scope and Contents
Contents
To identify the region(s) of the insulin receptor and the insulin-like growth factor I (IGF-I) receptor responsible for ligand specificity (high-affinity binding), expression vectors encoding soluble chimeric insulin/IGF-I receptors were prepared. The chimeric receptors were expressed in mammalian cells and partially purified. Binding studies revea...
Alternative Titles
Full title
The Ligand Specificities of the Insulin Receptor and the Insulin-Like Growth Factor I Receptor Reside in Different Regions of a Common Binding Site
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Record Identifier
TN_cdi_pnas_primary_88_10_4404
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_88_10_4404
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.88.10.4404
