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Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland expla...

Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland expla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_91_12_5232_fulltext

Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants

About this item

Full title

Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants

Publisher

United States: National Acad Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1994-06, Vol.91 (12), p.5232-5236

Language

English

Formats

Publication information

Publisher

United States: National Acad Sciences

More information

Scope and Contents

Contents

One of the earliest cellular responses to prolactin (PRL) binding in Nb2 cells, a rat pre-T lymphoma cell line, is an increase in tyrosine phosphorylation of cellular proteins. In this work, immunologic techniques have been used to demonstrate that in Nb2 cells and in mouse mammary gland explants, JAK2, a non-receptor tyrosine kinase, is activated...

Alternative Titles

Full title

Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_91_12_5232_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_91_12_5232_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.91.12.5232

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