Long-Term in vivo Expression of the Human Glucocerebrosidase Gene in Nonhuman Primates After CD34+He...
Long-Term in vivo Expression of the Human Glucocerebrosidase Gene in Nonhuman Primates After CD34+Hematopoietic Cell Transduction with Cell-Free Retroviral Vector Preparations
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences of the United States of America
Subjects
More information
Scope and Contents
Contents
Successful gene transfer into stem cells would provide a potentially useful therapeutic modality for treatment of inherited and acquired disorders affecting hematopoietic tissues. Coculture of primate bone marrow cells with retroviral producer cells, autologous stroma, or an engineered stromal cell line expressing human stem cell factor has resulte...
Alternative Titles
Full title
Long-Term in vivo Expression of the Human Glucocerebrosidase Gene in Nonhuman Primates After CD34+Hematopoietic Cell Transduction with Cell-Free Retroviral Vector Preparations
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_92_10_4372
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_92_10_4372
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.92.10.4372
