Serological Response Patterns of Melanoma Patients Immunized with a GM2 Ganglioside Conjugate Vaccin...
Serological Response Patterns of Melanoma Patients Immunized with a GM2 Ganglioside Conjugate Vaccine
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United States: National Academy of Sciences of the United States of America
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Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
Gangliosides, such as GM2, GD2, GD3, and 9-O-acetyl GD3, are receiving attention as targets for antibody-based and vaccine-based therapies of melanoma. GM2 appears to be a particularly immunogenic ganglioside in humans, as indicated by the presence of naturally occurring IgM anti-GM2 antibodies in ≈5% of humans and the fact that immunization with i...
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Full title
Serological Response Patterns of Melanoma Patients Immunized with a GM2 Ganglioside Conjugate Vaccine
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TN_cdi_pnas_primary_92_7_2805
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_92_7_2805
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.92.7.2805