Inhibition of Cyclin D-CDK4/CDK6 Activity is Associated with an E2F-Mediated Induction of Cyclin Kin...
Inhibition of Cyclin D-CDK4/CDK6 Activity is Associated with an E2F-Mediated Induction of Cyclin Kinase Inhibitor Activity
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
Alterations of various components of the cell cycle regulatory machinery that controls the progression of cells from a quiescent to a growing state contribute to the development of many human cancers. Such alterations include the deregulated expression of G1 cyclins, the loss of function of activities such as those of protein p16INK4a that control...
Alternative Titles
Full title
Inhibition of Cyclin D-CDK4/CDK6 Activity is Associated with an E2F-Mediated Induction of Cyclin Kinase Inhibitor Activity
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Record Identifier
TN_cdi_pnas_primary_93_9_4350
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_93_9_4350
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.93.9.4350
