Antigen Receptor Engagement Delivers a Stop Signal to Migrating T Lymphocytes
Antigen Receptor Engagement Delivers a Stop Signal to Migrating T Lymphocytes
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Publisher
United States: National Academy of Sciences of the United States of America
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Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
We investigated the role of the T cell antigen receptor (TcR) in control of T cell migration in an in vitro system. We used T cells from transgenic mice bearing a TcR for the lysozyme peptide 48-62 bound to I-Ak(3A9). T cells from the 3A9 TcR transgenic mice crawled on purified intercellular adhesion molecule-1 substrates, but strikingly, stopped u...
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Full title
Antigen Receptor Engagement Delivers a Stop Signal to Migrating T Lymphocytes
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TN_cdi_pnas_primary_94_8_3909_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_94_8_3909_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.94.8.3909
