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A 12R-Lipoxygenase in Human Skin: Mechanistic Evidence, Molecular Cloning, and Expression

A 12R-Lipoxygenase in Human Skin: Mechanistic Evidence, Molecular Cloning, and Expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_95_12_6744

A 12R-Lipoxygenase in Human Skin: Mechanistic Evidence, Molecular Cloning, and Expression

About this item

Full title

A 12R-Lipoxygenase in Human Skin: Mechanistic Evidence, Molecular Cloning, and Expression

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1998-06, Vol.95 (12), p.6744-6749

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

A recognized feature of psoriasis and other proliferative dermatoses is accumulation in the skin of the unusual arachidonic acid metabolite, 12R-hydroxyeicosatetraenoic acid (12R-HETE). This hydroxy fatty acid is opposite in chirality to the product of the well-known 12S-lipoxygenase and heretofore in mammals is known only as a product of cytochrom...

Alternative Titles

Full title

A 12R-Lipoxygenase in Human Skin: Mechanistic Evidence, Molecular Cloning, and Expression

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_95_12_6744

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_95_12_6744

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.95.12.6744

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