A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Ne...
A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Neuron-Specific Alternative Splicing
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United States: National Academy of Sciences of the United States of America
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Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
The Nova paraneoplastic antigens are neuron-specific RNA binding proteins that participate in the control of alternative splicing. We have used the yeast two-hybrid system to isolate Nova interacting proteins and identify an RNA binding protein that is closely related to the polypyrimidine tract-binding protein (PTB). The expression of this protein...
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Full title
A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Neuron-Specific Alternative Splicing
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TN_cdi_pnas_primary_97_12_6350
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_97_12_6350
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.110128397