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A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Ne...

A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Ne...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_97_12_6350

A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Neuron-Specific Alternative Splicing

About this item

Full title

A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Neuron-Specific Alternative Splicing

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-06, Vol.97 (12), p.6350-6355

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

The Nova paraneoplastic antigens are neuron-specific RNA binding proteins that participate in the control of alternative splicing. We have used the yeast two-hybrid system to isolate Nova interacting proteins and identify an RNA binding protein that is closely related to the polypyrimidine tract-binding protein (PTB). The expression of this protein...

Alternative Titles

Full title

A Brain-Enriched Polypyrimidine Tract-Binding Protein Antagonizes the Ability of Nova to Regulate Neuron-Specific Alternative Splicing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_97_12_6350

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_97_12_6350

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.110128397

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