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The State Diagram for Cell Adhesion Under Flow: Leukocyte Rolling and Firm Adhesion

The State Diagram for Cell Adhesion Under Flow: Leukocyte Rolling and Firm Adhesion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_97_21_11262

The State Diagram for Cell Adhesion Under Flow: Leukocyte Rolling and Firm Adhesion

About this item

Full title

The State Diagram for Cell Adhesion Under Flow: Leukocyte Rolling and Firm Adhesion

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (21), p.11262-11267

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Leukocyte adhesion under flow in the microvasculature is mediated by binding between cell surface receptors and complementary ligands expressed on the surface of the endothelium. Leukocytes adhere to endothelium in a two-step mechanism: rolling (primarily mediated by selectins) followed by firm adhesion (primarily mediated by integrins). Using a co...

Alternative Titles

Full title

The State Diagram for Cell Adhesion Under Flow: Leukocyte Rolling and Firm Adhesion

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_97_21_11262

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_97_21_11262

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.200240897

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