Tolerance of Human MSH2+/-Lymphoblastoid Cells to the Methylating Agent Temozolomide
Tolerance of Human MSH2+/-Lymphoblastoid Cells to the Methylating Agent Temozolomide
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Members of hereditary nonpolyposis colon cancer (HNPCC) families harboring heterozygous germline mutations in the DNA mismatch repair genes hMSH2 or hMLH1 present with tumors generally two to three decades earlier than individuals with nonfamilial sporadic colon cancer. We searched for phenotypic features that might predispose heterozygous cells fr...
Alternative Titles
Full title
Tolerance of Human MSH2+/-Lymphoblastoid Cells to the Methylating Agent Temozolomide
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Record Identifier
TN_cdi_pnas_primary_98_13_7164_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_98_13_7164_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.121136498
