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Caspase-10 is an Initiator Caspase in Death Receptor Signaling

Caspase-10 is an Initiator Caspase in Death Receptor Signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_98_24_13884_fulltext

Caspase-10 is an Initiator Caspase in Death Receptor Signaling

About this item

Full title

Caspase-10 is an Initiator Caspase in Death Receptor Signaling

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.13884-13888

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

A role for caspase-10, previously implicated in the autoimmune lymphoproliferative syndrome, in death receptor signaling has not been directly shown. Here we show that caspase-10 can function independently of caspase-8 in initiating Fas- and tumor necrosis factor-related apoptosis-inducing ligand-receptor-mediated apoptosis. Moreover, Fas crosslink...

Alternative Titles

Full title

Caspase-10 is an Initiator Caspase in Death Receptor Signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_98_24_13884_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_98_24_13884_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.241358198

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