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Interaction of Gα12 with Gα13 and Gαq Signaling Pathways

Interaction of Gα12 with Gα13 and Gαq Signaling Pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_99_14_9352_fulltext

Interaction of Gα12 with Gα13 and Gαq Signaling Pathways

About this item

Full title

Interaction of Gα12 with Gα13 and Gαq Signaling Pathways

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (14), p.9352-9357

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

The G12 subfamily of heterotrimeric G-proteins consists of two members, G12 and G13. Gene-targeting studies have revealed a role for G13 in blood vessel development. Mice lacking the α subunit of G13 die around embryonic day 10 as the result of an angiogenic defect. On the other hand, the physiological role of G12 is still unclear. To address this...

Alternative Titles

Full title

Interaction of Gα12 with Gα13 and Gαq Signaling Pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_99_14_9352_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_99_14_9352_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.102291599

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