Myristoylation as a Target for Inhibiting HIV Assembly: Unsaturated Fatty Acids Block Viral Budding
Myristoylation as a Target for Inhibiting HIV Assembly: Unsaturated Fatty Acids Block Viral Budding
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Modification of HIV-1 Gag with myristic acid, a saturated 14-carbon fatty acid (14:0), is essential for HIV-1 assembly. We recently showed that exogenous treatment of cells with unsaturated 14-carbon fatty acids, 5-cis-tetradecenoic acid (14:1n-9) and 5-cis,8-cis-tetradecadienoic acid (14:2n-6), reduces the affinity of some myristoylated proteins f...
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Myristoylation as a Target for Inhibiting HIV Assembly: Unsaturated Fatty Acids Block Viral Budding
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TN_cdi_pnas_primary_99_20_13037
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_99_20_13037
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.212409999
