Directed Evolution of the Site Specificity of Cre Recombinase
Directed Evolution of the Site Specificity of Cre Recombinase
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Cre recombinase from bacteriophage P1 recognizes a 34-bp recombination site, loxP, with exquisite sequence specificity and catalyzes the site-specific insertion, excision, or rearrangement of DNA. To better understand the molecular basis of protein-DNA recognition and generate recombinases with altered specificities, we have developed a directed ev...
Alternative Titles
Full title
Directed Evolution of the Site Specificity of Cre Recombinase
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_99_7_4185
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_99_7_4185
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.022039799
