miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
This report identifies a new contribution of members of the miR-200 family to tumorigenesis. miR-200a and miR-141 specifically regulate p38α, contributing to the cellular modulation of oxidative stress responses. In this role, the miRs can accelerate ovarian tumorigenesis but also endow cancer cells with increased sensitivity to ROS-inducing chemot...
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miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
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TN_cdi_proquest_journals_1009160928
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1009160928
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2512