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Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic...

Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1013451695

Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress

About this item

Full title

Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Diabetologia, 2012-05, Vol.55 (5), p.1366-1379

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Aims/hypothesis
Endoplasmic reticulum (ER) stress has been implicated in glucose-induced beta cell dysfunction. However, its causal role has not been established in vivo. Our objective was to determine the causal role of ER stress and its link to oxidative stress in glucose-induced beta cell dysfunction in vivo.
Methods
Healthy Wistar rats...

Alternative Titles

Full title

Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1013451695

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1013451695

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-012-2474-8

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