Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic...
Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress
About this item
Full title
Author / Creator
Tang, C. , Koulajian, K. , Schuiki, I. , Zhang, L. , Desai, T. , Ivovic, A. , Wang, P. , Robson-Doucette, C. , Wheeler, M. B. , Minassian, B. , Volchuk, A. and Giacca, A.
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Aims/hypothesis
Endoplasmic reticulum (ER) stress has been implicated in glucose-induced beta cell dysfunction. However, its causal role has not been established in vivo. Our objective was to determine the causal role of ER stress and its link to oxidative stress in glucose-induced beta cell dysfunction in vivo.
Methods
Healthy Wistar rats...
Alternative Titles
Full title
Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1013451695
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1013451695
Other Identifiers
ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-012-2474-8
